Abstract: The main objectives of soil and water conservation in Danjiangkou Reservoir area and its upper reaches in the thirteenth five-year plan are mitigating soil and water loss, improving water conservation capacity and controlling non-point source pollution. Based on the information collected from different counties in the study area as well as the data from the first national geographic information census in 2015, high-resolution RS image data, basic geographical information data and materials on special topics, we obtained the planned data in different scales. By selecting the indexes of population density, water resources amount, total Nitrogen concentration, cultivation index, proportion of sloping farmland, forest-grass covering ratio, proportion of soil and water loss area; and then by conducting comprehensive analysis of index weight, we could rank the forty three controlling zones, and determine nineteen control units as the key regions for the water and soil conservation plan. The results provide important basis for scientific planning of soil and water conservation in the reservoir area.