Abstract: In 2017, the water entering Danjiangkou Reservoir was slightly greater than normal, but uneven in flood season and changed rapidly from flood to dry. We were faced problems that outstanding contradiction between flood control and water supply, and the reservoir did not subject to severe high water level. In order to improve the comprehensive utilization efficiency of water resources, and ensure the comprehensive benefits of flood control and water supply for the reservoir，we carried out refine dispatching in the light of different stages, i.e. dam transverse joint disposal period, autumn flood control period and 167m storage period at the end of flood season. Through adopting the measures of formulating fine dispatching schemes, strengthening forecast, holding intensive consultation, 24-hour real-time standby of power plant personnel, intensifying water level monitoring, warning in advance, etc., the reservoir safety was ensured in the flood season, with 704 million yuan of flood control benefit achieved. The 167m water storage check and acceptance work of the reservoir was successfully completed after the flood. The total water supply to the north region exceeded 10 billion m3 through S-N water diversion project with reaching the design discharge of 350 m3/s for the first time. In addition, the annual power generation reached 3.123 billion kW.h. Above all show the remarkable benefits of the reservoir in flood control, water supply and power generation.