Abstract: In order to optimize the joint operation scheme of flood control projects such as river channel, flood detention area and flood diversion channel, etc, a one-two dimensional coupled hydrodynamic numerical model from Honghekou to Xiaoliuxiang of Huaihe River was established on the basis of evolution law of the middle regular flood. Taking the 2003 flood as an example, the influence of number and sequence of using flood control projects on flood peak water level and flood duration were simulated under the current and planned conditions. The results showed that(1)under the current conditions and the same number of flood diversion measures in service, the calculated water level was lower than that in 2003 and the duration of high water level was shorter than that in 2003 by taking dispatch scheme optimization.(2)Under the planning condition, the water level in most reaches was lower than the guaranteed value just by putting Mengwa detention area and Jiangtanghu flooding area into operation, demonstrating that the effect of the river regulation and flood-detention adjustment would be significant. On the basis of typical flood regulation in 2003, the regulation principles of flood detention area and flood diversion channel were put forward as follow: the using sequence of flood diversion measures should be at this section first, then upstream reach and downstream reach last, besides, putting flood diversion into operation firstly, then flooding routing measures, and flood detention last.