Abstract: In order to study the treatment effect of the black-odor water body in Qingdao City, the comprehensive treatment project for black-odor water of Loushan River was taken as an example. In the first on-site investigation, pollution problems such as disorder point source pollution, rain and sewage mixed flow, unconnected pipe networks, sediment deposition etc, were found. Combined with the current drainage system in the old industrial urban area and the collected historical data, engineering measures were proposed. These measures included three technical routes in terms of water safety(water conservancy measures), water environment(municipal engineering measures) and water ecology(environmental engineering measures). The water conservancy measures included sediment dredging and embankment protection shore, municipal engineering measures included improvement of rainwater pipe network and water system planning, and environmental engineering measures included sediment treatment and green space system construction. Then the second-stage treatment effect was investigated. The investigation showed that the concentration of the water quality indices was lower than the water quality standard of moderate black-odor water, indicating the treatment achieved a phased success. This practical case can provide engineering references for the comprehensive treatment of the black-odor water.