Abstract: Coreius guichenoti(Sauvage et Dabry) is a national second-class key protected wild animal and an endemic fish in the upper reaches of the Yangtze River.It is a typical freshwater migratory fish in China.It is of great significance to study the resource changes of C.guichenoti under the construction of cascade hydropower stations for the protection of C.guichenoti.Based on the results of literature research and field monitoring, we found that the resources of C.guichenoti showed a downward trend, and the distribution range was reduced and fragmented with the damming.Generally, after several years of impoundment, there is no clue of C.guichenoti in the reservoir area, but any trail of this fish can be found at downstream flowing channel of the dam.At present the broodstock can be monitored only at the section of Dongchuan ferry under the Wudongde Dam in the lower reaches of the Jinsha River.The spawning scale of C.guichenoti monitored in the Panzhihua, Jiaopingdu and Qiaojia sections decreased significantly.Based on the review of research on the resource changes of C.guichenoti,it is suggested to strengthen the protection of habitats and spawning grounds, and construct the artificial spawning grounds; carry out genetic management for the artificial population of C.guichenoti and strengthen the research on the evaluation of the release effect; build fish passage facilities so that C.guichenoti can successfully pass through dams and other artificial obstacles to complete reproductive migration.