Abstract: To improve the level of water resources-economy-ecological resilience in the arid region of Xinjiang and achieve the coordinated development of the three, taking 14 prefectures in the arid zone of Xinjiang as examples, the entropy weight method was used to determine the weights of indicators, and the coupling coordination model was applied to measure the water resources-economy-ecological resilience coupling degree and coordination degree.The R/S analysis was applied to predict the development trend of the future coordination degree in Xinjiang.The results showed that:(1) From 2010 to 2020,the overall development level of the water resources-economy-ecological resilience in Xinjiang showed an upward trend, and the system′s resistance, resilience and adaptability to risk were enhanced.(2) The coupling degree of each region and prefectures was in a good state, and the overall coordination level has changed from barely coordinated to intermediate out of balance.(3) From the Hurst index, 9 regions including Bortala Mongol Autonomous Prefecture, showed an improving trend in water resources-economy-ecological resilience coordination, and 5 regions including Changji Hui Autonomous Prefecture, showed a deteriorating trend in coordination.Xinjiang should pay attention to the protection of water resources and ecological environment in the future development, improve the coordination degree of water resources-economy-ecological resilience, and realize the sustainable development of the society.